Cutaneous granulocytic sarcoma and Koebner phenomenon in a context of myelodysplastic syndrome
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Cutaneous granulocytic sarcoma and Koebner phenomenon in a context of myelodysplastic syndrome
CGS: cutaneous granulocytic sarcoma GS: granulocytic sarcoma IHC: immunohistochemistry KP: Koebner phenomenon MDS: myelodysplastic syndrome MPO: myeloperoxidase PG: pyoderma gangrenosum TGF-b1: transforming growth factor-beta 1 TGF-b1R: transforming growth factor-beta 1 receptor INTRODUCTION Granulocytic sarcoma (GS) is also known as myeloid sarcoma or chloroma because of its green hue caused b...
متن کاملAn unusual cutaneous manifestation of myelodysplastic syndrome: "pseudo-Koebner phenomenon".
An unusual and hitherto unreported complication of myelodysplastic syndrome is reported: the "pseudo-Koebner phenomenon." The skin lesions were characterised by exuberant "fleshy" masses at the sites of intravenous cannulation and skin trauma, and by histological evidence of chronic inflammation with focal necrosis and abscess formation. No evidence of dermal infiltration by malignant haemopoie...
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Granulocytic sarcoma (GS) is an uncommon and localized extramedullary tumor composed of immature granulocytic cells. Most GS reported in large series were not associated with overt acute myelogenous leukemia. Gastric perforation occurred during prednisolone therapy in a 72-year-old Japanese male with a four-month history of a myelofibrosis-like state. Subtotal gastrectomy was performed for a su...
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Granulocytic sarcomas (GS) are uncommon extramedullary tumors composed of immature cells of the granulocytic or myeloid series. Treatment for GS should be directed toward the underlying hematologic disorder. There is no standard treatment. Granulocytic sarcoma (GS) is seen in ~5% of myeloid leukemia cases and represents the "tissue phase" of the disease. GS can also be seen in patients with chr...
متن کاملA Case of Granulocytic Sarcoma of the Brain in a Patient with Myelodysplastic Syndrome
Granulocytic sarcoma is rare extramedullary tumor composed of myeloblasts and other granulocytic precursors. The majority of cases have been reported in association with acute myeloid leukemia (AML) or myeloproliferative disorders. Granulocytic sarcoma may occur in patients with myelodysplastic syndromes. Reports are very rare, especially in the brain. We report an unusual case of granulocytic ...
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ژورنال
عنوان ژورنال: JAAD Case Reports
سال: 2015
ISSN: 2352-5126
DOI: 10.1016/j.jdcr.2015.04.012